Spider leg veins arecommon. Their treatment with laser or intensed light therapy shows generally variable success rates and often adverse side effects such ashyper- or hypopigmentation. This study was performed to investigate whether pulsed diode laser (810 nm)treatment is effective and safe.
METHODS:
Thirty-five female patientswith spider leg veins were includedin this prospective trial. They were treated twice with a pulsed diodelaser (810 nm). Laser therapy was performed on day 0 and day 14. Clinical assessments were before an carried out immediately after the first laser therapy, after 2 weeks, 8weeks, and one year. Skin biopsies were taken before and immediately after the first laser treatment, and after 10 weeks. Contact-free remittance spectroscopy was performed before laser treatment, immediately after the first treatment, after 2weeks and 8 weeks.
RESULTS: After the first treatment 15patients showed a complete disappearance(CR); in the remaining 20 patients a remarkable improvement (RI) was noted (n~35). After six months of follow-up CR was seen in 6 patients, RI in 6, a stable situationin 9, and scar formation in 1 patient(n~21). The effect was almost completely stable during one year offollow-up. The examination of histologicalspecimens before and afterlaser treatment showed no cellularin flammatory reaction. The mean vascular area was significantly reduced after the first (p,0.05) and after the second (p,0.05) laser treatment. Spectral analysis showed a marked decrease of peaks for oxygenized haemoglobin immediately after laser treatment and during thefollow-up. Safety profile was excellent without purpuric reaction orpigmentary changes. Mild scarringwas observed in two patients at theend of follow-up.
CONCLUSIONS:
Pulsed diode laser therapy (810 nm) is an effective and safe treatment option for spider legveins. The effects can be seen immediately.Objective monitoring by non-invasive remission spectroscopy and histology of biopsy specimens demonstrates selectivity of the laser action.
donna@gigaalaser.com
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